in situ

adverb or adjective

in si·​tu (ˌ)in-ˈsī-(ˌ)tü How to pronounce in situ (audio)
-ˈsi-
-(ˌ)tyü How to pronounce in situ (audio)
also -ˈsē-
-(ˌ)chü How to pronounce in situ (audio)
: in the natural or original position or place
an in situ cancer confined to the breast duct

Examples of in situ in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
To delineate the murine C3aR coding sequence, gene structure, 5′-flanking region, and chromosome location, cDNA and genomic clones encoding the mouse C3a receptor were isolated, characterized, and used in fluorescence in situ hybridization experiments. Kirstin R.w. Matthews, STAT, 3 Feb. 2026 Abraham was in situ and the challenge of filling this transfer window’s priority position, which had brought so much turbulence, had been met. Jacob Tanswell, New York Times, 27 Jan. 2026 Against a background of learning, characters are shaped in situ. Literary Hub, 16 Jan. 2026 It also couldn’t be repaired in situ. Christopher McFadden, Interesting Engineering, 11 Jan. 2026 See All Example Sentences for in situ

Word History

Etymology

Latin, in position

First Known Use

1740, in the meaning defined above

Time Traveler
The first known use of in situ was in 1740

Browse Nearby Words

Cite this Entry

“In situ.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/in%20situ. Accessed 6 Feb. 2026.

Kids Definition

in situ

adverb or adjective
in si·​tu (ˈ)in-ˈsī-t(y)ü How to pronounce in situ (audio)
-ˈsi-
: in the natural or original position
the cancer cells remained in situ
Etymology

Latin, "in position"

Medical Definition

in situ

adverb or adjective
in si·​tu
(ˈ)in-ˈsī-(ˌ)t(y)ü, -ˈsi- also -ˈsē-, -(ˌ)chü
: in the natural or original position or place
an in situ cancer confined to the breast duct
see carcinoma in situ
Last Updated: - Updated example sentences
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